N-BOC INDOLE
1-Boc-indole
CAS: 75400-67-8
Molecular Formula: C13H15NO2
N-BOC INDOLE - Names and Identifiers
| Name | 1-Boc-indole |
| Synonyms | 127818 1-Boc-indole N-BOC INDOLE 1-BOC-INDOLE INDOLE, BOC PROTECTED Indole, N-BOC protected 1-(TERT-BUTOXYCARBONYL)INDOLE 1-(tert-Butoxycarbonyl)indole tert-Butyl 1-indolecarboxylate TERT-BUTYL 1-INDOLECARBOXYLATE TERT-BUTYL 1H-INDOLE-1-CARBOXYLATE tert-butyl 1H-indole-1-carboxylate |
| CAS | 75400-67-8 |
| EINECS | 806-633-6 |
| InChI | InChI=1/C13H15NO2/c1-13(2,3)16-12(15)14-9-8-10-6-4-5-7-11(10)14/h4-9H,1-3H3 |
N-BOC INDOLE - Physico-chemical Properties
| Molecular Formula | C13H15NO2 |
| Molar Mass | 217.26 |
| Density | 1.07g/mLat 25°C(lit.) |
| Melting Point | 24-26 |
| Boling Point | 201°C(lit.) |
| Flash Point | 160°F |
| Vapor Presure | 0.000368mmHg at 25°C |
| Specific Gravity | 1.070 |
| BRN | 4674239 |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | n20/D 1.543(lit.) |
| MDL | MFCD02093939 |
N-BOC INDOLE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| Hazard Note | Irritant/Keep Cold |
| Hazard Class | IRRITANT, KEEP COLD |
N-BOC INDOLE - Introduction
1-Boc-indole(1-Boc-indole) is an organic compound with the chemical formula C14H19NO2. It is a Boc protecting group (tert-butoxycarbonyl) substitution of indole.
Nature:
1-Boc-indole is a white to yellow crystalline solid that is stable at ambient temperature. It has a high melting point and boiling point, soluble in some organic solvents such as chloroform and dichloromethane, insoluble in water.
Use:
1-Boc-indole is often used as an intermediate in organic synthesis. It can be used to synthesize various indole derivatives, such as drugs, dyes and polymers. 1-Boc-indole can also be used as a protecting group for organic synthesis reactions to protect reactive functional groups on the indole.
Preparation Method:
1-Boc-indole is generally prepared by reacting 1,2-indole with Boc-OSu(tert-butyloxycarbonyl-N-hydroxysuccinimide). The specific method can refer to the organic synthesis literature.
Safety Information:
1-Boc-indole is relatively safe for human health under normal operating conditions. However, it is still a chemical, and care should be taken to avoid contact with skin, eyes and respiratory tract, and appropriate protective measures should be worn when using it. Follow relevant safety standards and operating procedures during storage and handling. Waste shall be disposed of in accordance with relevant laws and regulations.
Nature:
1-Boc-indole is a white to yellow crystalline solid that is stable at ambient temperature. It has a high melting point and boiling point, soluble in some organic solvents such as chloroform and dichloromethane, insoluble in water.
Use:
1-Boc-indole is often used as an intermediate in organic synthesis. It can be used to synthesize various indole derivatives, such as drugs, dyes and polymers. 1-Boc-indole can also be used as a protecting group for organic synthesis reactions to protect reactive functional groups on the indole.
Preparation Method:
1-Boc-indole is generally prepared by reacting 1,2-indole with Boc-OSu(tert-butyloxycarbonyl-N-hydroxysuccinimide). The specific method can refer to the organic synthesis literature.
Safety Information:
1-Boc-indole is relatively safe for human health under normal operating conditions. However, it is still a chemical, and care should be taken to avoid contact with skin, eyes and respiratory tract, and appropriate protective measures should be worn when using it. Follow relevant safety standards and operating procedures during storage and handling. Waste shall be disposed of in accordance with relevant laws and regulations.
Last Update：2024-04-09 19:05:52
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